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Genome-wide expression profiling of B Lymphocytes reveals IL4R increase in allergic asthma

ABSTRACT: In this study we present the first genome-wide expression profiling of peripheral B cells by massive parallel RNA sequencing in patients with allergic asthma validating the discovery potential of this approach in allergy. RNA-seq was used to asses expression differences in B CD19 Lymphocytes from house dust mite allergic patients and healthy controls.

ORGANISM(S): Homo sapiens

SUBMITTER: SERGIO ROA

PROVIDER: E-GEOD-52742 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genome-wide expression profiling of B lymphocytes reveals IL4R increase in allergic asthma.

Pascual Marien M Roa Sergio S García-Sánchez Asunción A Sanz Catalina C Hernandez-Hernandez Laura L Greally John M JM Lorente Félix F Dávila Ignacio I Isidoro-García María M

The Journal of allergy and clinical immunology 20140626 4

PMID: 24975796

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