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Copy number variation comparison between control and CC214-2 resistant GBM39 xenografts

ABSTRACT: Here we present genome-wide copy number variation data on two vehicle treated and two CC214-2 (an mTOR kinase inhibitor) resistant GlioBlastoma Multiforme 39 (GBM39) xenografts, showing the absence of significant differences between the two groups, demonstrating that resistance to CC214-2 is due to adaptation rather than gene mutations. The genomic DNA extracted from the 4 xenografts samples was analysed with genome-wide Affymetrix SNP6.0 array

ORGANISM(S): Homo sapiens

SUBMITTER: Paul Mischel

PROVIDER: E-GEOD-53042 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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