Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Alexander Balbir
PROVIDER: E-GEOD-5313 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
American journal of physiology. Lung cellular and molecular physiology 20061110 3
The carotid body (CB) is the primary hypoxic chemosensory organ. Its hypoxic response appears to be genetically controlled. We have hypothesized that: 1) genes related to CB function are expressed less in the A/J mice (low responder to hypoxia) compared with DBA/2J mice (high responder to hypoxia); and 2) gene expression levels of morphogenic and trophic factors of the CB are significantly lower in the A/J mice than DBA/2J mice. This study utilizes microarray analysis to test these hypotheses. T ...[more]