Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Rebekah Karns
PROVIDER: E-GEOD-53782 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nature 20140326 7499
Bariatric surgical procedures, such as vertical sleeve gastrectomy (VSG), are at present the most effective therapy for the treatment of obesity, and are associated with considerable improvements in co-morbidities, including type-2 diabetes mellitus. The underlying molecular mechanisms contributing to these benefits remain largely undetermined, despite offering the potential to reveal new targets for therapeutic intervention. Substantial changes in circulating total bile acids are known to occur ...[more]