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RNAseq Analysis of Mouse Stomach and Intestines Following Vertical Sleeve Gastrectomy

ABSTRACT: Bariatric surgery, an effective treatment for obesity and diabetes, leads to profound remodeling of whole body energy homeostasis. We utilized a mouse model of vertical sleeve gastrectomy (VSG), a common bariatric surgery as a tool to identify novel secreted proteins and peptides that might act as important metabolic regulators. We analyzed gene expression in the stomach and intestines following VSG or sham surgery in diet-induced obese mice and sought to identify differentially regulated genes encoding secreted proteins/peptides.

ORGANISM(S): Mus musculus

PROVIDER: GSE104956 | GEO | 2017/10/14

SECONDARY ACCESSION(S): PRJNA414231

REPOSITORIES: GEO

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Gene expression profiling of the ileum following vertical sleeve gastrectomy compared to pair-fed sham surgery controls in mice with high-fat diet-induced obesity.

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