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Transcription profiling of Drosophila selected for aggressive behavior over 28 generations vs controls

ABSTRACT: Genes relevant to manifestion of and variation in aggression behavior might be differentially expressed in lines selected for divergent levels of aggression. Experiment Overall Design: Drosophila males were assessed for their aggression levels in a behavioral assay that quantified aggressive encounters. A subset of the sampled population was selected as parents for the next generation, with High, Low, and Control selection groups maintained. This artificial selection was continued for 28 generations, with a variety of other behavioral and life history traits assessed for correlation with response to selection for aggression. At generation 28, male and female flies were collected for RNA extraction and subsequent gene expression analysis.

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Alexis Edwards

PROVIDER: E-GEOD-5404 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Quantitative genomics of aggressive behavior in Drosophila melanogaster.

Edwards Alexis C AC Rollmann Stephanie M SM Morgan Theodore J TJ Mackay Trudy F C TF

PLoS genetics 20060802 9

Aggressive behavior is important for animal survival and reproduction, and excessive aggression is an enormous social and economic burden for human society. Although the role of biogenic amines in modulating aggressive behavior is well characterized, other genetic mechanisms affecting this complex behavior remain elusive. Here, we developed an assay to rapidly quantify aggressive behavior in Drosophila melanogaster, and generated replicate selection lines with divergent levels of aggression. The ...[more]

PMID: 17044737

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