Over-expression of either MECP2_e1 or MECP2_e2 in neuronally differentiated cells (SK-N-SH)
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ABSTRACT: Aim: to detect genes that are differentially transcribed in neuronal cells(SK-N-SH) over-expressing either of the two MECP2 isoforms, MECP2_e1 or MECP2_e2. Methods: the human neuroblastoma cell line SK-N-SH was stably infected by lentiviral vectors over-expressing MECP2_e1, MECP2_e2, or eGFP, and were then differentiated into neurons. RNA extracted, and used for gene expression microarray analysis 3 replicates for MECP2_e1; 3 replicates for MECP2_e2; 3 replicates for eGFP as control; 3 replicates for MECP2_e1 with 9bp insertion mutation in N-terminal
ORGANISM(S): Homo sapiens
SUBMITTER: john vincent
PROVIDER: E-GEOD-54258 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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