Transcription array by profiling in WT and SRC-2 null mouse liver
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Jae-Wook Jeong
PROVIDER: E-GEOD-55002 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.
Jeong Jae-Wook JW Kwak Inseok I Lee Kevin Y KY White Lisa D LD Wang Xiao-Ping XP Brunicardi F C FC O'Malley Bert W BW DeMayo Francesco J FJ
Molecular endocrinology (Baltimore, Md.) 20060119 5
Members of the steroid receptor coactivator (SRC) family, which include SRC-1 (NcoA-1/p160), SRC-2(TIF2/GRIP1/NcoA-2) and SRC-3(pCIP/RAC3/ACTR/pCIP/ AIB1/TRAM1), are critical mediators of steroid receptor action. Gene ablation studies previously identified SRC-1 and SRC-2 as being involved in the control of energy homeostasis. A more precise identification of the molecular pathways regulated by these coactivators is crucial for understanding the role of steroid receptor coactivators in the contr ...[more]
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