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Transcriptomic characterization of Hepatocellular Carcinoma with CTNNB1 mutation

ABSTRACT: We report transcritomic characterization of changes in CTNNB1 mutation positive HCCs in comparison to paratumoral tissues 4 pair of HCC and paratumoral liver tissues are sequenced and compared

ORGANISM(S): Homo sapiens

SUBMITTER: Tao Cai

PROVIDER: E-GEOD-55048 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptomic characterization of hepatocellular carcinoma with CTNNB1 mutation.

Ding Xiao X Yang Yuan Y Han Baoda B Du Chengzhi C Xu Naiqing N Huang Huanwei H Cai Tao T Zhang Aiqun A Han Ze-Guang ZG Zhou Weiping W Chen Liang L

PloS one 20140505 5

<h4>Purpose</h4>Hepatocellular carcinoma (HCC) is the sixth most common solid tumor worldwide and the third leading cause of cancer-related death. HCC is a particularly serious threat to the Chinese population. Although many molecular alterations are known to be involved in the tumorigenesis of hepatocytes, no systemic survey has examined the somatic mutations in HCC samples from Chinese patients. Our goal was to elucidate somatic mutations in Chinese HCC patients and investigate the possible mo ...[more]

PMID: 24798046

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