Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Sarah Poulsen
PROVIDER: E-GEOD-55286 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Poulsen Sarah S SS Saber Anne T AT Williams Andrew A Andersen Ole O Købler Carsten C Atluri Rambabu R Pozzebon Maria E ME Mucelli Stefano P SP Simion Monica M Rickerby David D Mortensen Alicja A Jackson Petra P Kyjovska Zdenka O ZO Mølhave Kristian K Jacobsen Nicklas R NR Jensen Keld A KA Yauk Carole L CL Yauk Carole L CL Wallin Håkan H Halappanavar Sabina S Vogel Ulla U
Toxicology and applied pharmacology 20141229 1
Multi-walled carbon nanotubes (MWCNTs) are an inhomogeneous group of nanomaterials that vary in lengths, shapes and types of metal contamination, which makes hazard evaluation difficult. Here we present a toxicogenomic analysis of female C57BL/6 mouse lungs following a single intratracheal instillation of 0, 18, 54 or 162 μg/mouse of a small, curled (CNT(Small), 0.8 ± 0.1 μm in length) or large, thick MWCNT (CNT(Large), 4 ± 0.4 μm in length). The two MWCNTs were extensively characterized by SEM ...[more]