Transcription profiling of human aortic endothelial cells treated with with oligomeric procyanidins extracts
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ABSTRACT: Human aortic endothelial cells were grown in culture until confluent. In three experiments using cells derived from three separate donors confluent cultures were incubated for 6 h with contol medium, or medium containing either extracts of oligomeric procyanidins from cranberry juice or red wine, or a procyanidin-rich grape seed extract. At the end of the 6 h treatment period conditioned media samples were retained for immunoassay of secreted peptides and proteins, and RNA was extracted for microarray analysis. Experiment Overall Design: Each experiment used cells from one donor. Treatment conditions were: control medium, cranberry extract (CRE), grape seed extract (GSE), and red wine extract (RWE).
ORGANISM(S): Homo sapiens
SUBMITTER: Roger Corder
PROVIDER: E-GEOD-5556 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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