Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Su(Hw) and Shep RIP-seq in Kc and BG3 cell lines


ABSTRACT: Su(Hw) and Shep RIP-seq in Kc and BG3 cell lines RIP-seq with multiple antibodies to two proteins in two Drosophila cell lines, at least 2 replicates for each IP and input

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Ryan Dale 

PROVIDER: E-GEOD-55894 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

metaseq: a Python package for integrative genome-wide analysis reveals relationships between chromatin insulators and associated nuclear mRNA.

Dale Ryan K RK   Matzat Leah H LH   Lei Elissa P EP  

Nucleic acids research 20140724 14


Here we introduce metaseq, a software library written in Python, which enables loading multiple genomic data formats into standard Python data structures and allows flexible, customized manipulation and visualization of data from high-throughput sequencing studies. We demonstrate its practical use by analyzing multiple datasets related to chromatin insulators, which are DNA-protein complexes proposed to organize the genome into distinct transcriptional domains. Recent studies in Drosophila and m  ...[more]

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