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Comparison of haploid and diploid clones of KBM7 cancer cell line


ABSTRACT: The series were performed to study the changes in gene expression upon diploidization of KBM7 cancer (CML) cell line. The line can exist either as a clone with 24 chromosomes (nearly haploid) or with 48 chromosomes (nearly diploid). Gene expression patterns are largely ploidy-independent, as suggested by this experiment Single cell derived clones of KBM7 cell line were grown. Included 7 haploid and 10 diploid clones, each with 2 independent total RNA extraction/microarray run. Also included peripheral blood mononuclear cells (PBMC) samples for comparison purposes.

ORGANISM(S): Homo sapiens

SUBMITTER: Yegor Smurnyy 

PROVIDER: E-GEOD-56465 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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