Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Daniel Hyduke
PROVIDER: E-GEOD-57196 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland.
Datta Kamal K Hyduke Daniel R DR Suman Shubhankar S Moon Bo-Hyun BH Johnson Michael D MD Fornace Albert J AJ
Radiation oncology (London, England) 20121205
<h4>Background</h4>Breast tissue is among the most sensitive tissues to the carcinogenic actions of ionizing radiation and epidemiological studies have linked radiation exposure to breast cancer. Currently, molecular understanding of radiation carcinogenesis in mammary gland is hindered due to the scarcity of in vivo long-term follow up data. We undertook this study to delineate radiation-induced persistent alterations in gene expression in mouse mammary glands 2-month after radiation exposure.< ...[more]
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