Gene expression profile of idiopathic thrombocytopenic purpura (ITP)
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Ruchira Sood
PROVIDER: E-GEOD-5812 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene expression profile of idiopathic thrombocytopenic purpura (ITP).
Sood Ruchira R Wong Wendy W Jeng Michael M Zehnder James L JL
Pediatric blood & cancer 20061001 5 Suppl
To search for novel mechanisms that contribute to the pathophysiology of idiopathic thrombocytopenic purpura (ITP), we determined the whole blood gene expression profile in five ITP patients and five control samples. Using DNA microarrays that contained 24,473 unique putative genes, we found 176 cDNAs that were strongly correlated with ITP. These included a cluster of interferon-regulated genes and TLR7, as well many less-well characterized genes which are candidates for further study. We believ ...[more]
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