Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Stefan Ambs
PROVIDER: E-GEOD-5847 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Boersma Brenda J BJ Reimers Mark M Yi Ming M Ludwig Joseph A JA Luke Brian T BT Stephens Robert M RM Yfantis Harry G HG Lee Dong H DH Weinstein John N JN Ambs Stefan S
International journal of cancer 20080301 6
The factors that determine whether a breast carcinoma will develop into inflammatory breast cancer (IBC) remain poorly understood. Recent evidence indicates that the tumor stroma influences cancer phenotypes. We tested the hypotheses that the gene expression signature of the tumor stroma is a distinctive feature of IBC. We used laser capture microdissection to obtain enriched populations of tumor epithelial cells and adjacent stromal cells from 15 patients with IBC and 35 patients with invasive, ...[more]