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The microRNA-200 family regulates pancreatic beta-cell survival in type 2 diabetes (islet)

ABSTRACT: Islets from control and beta-cell specific miR-141/200c overexpressing mice were extracted and Affymetrix gene expression analysis performed We used Affymetrix Chip analysis to address which genes are regulated upon miR-200-overexpression in beta-cells at the age of 6 weeks. Transgenic mice overexpressing miR-141/200c and control mice were subjected to islet extraction, RNA was extracted using Trizol method, and Affymetrix analysis was performed.

ORGANISM(S): Mus musculus

SUBMITTER: Lennart Opitz

PROVIDER: E-GEOD-58488 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The microRNA-200 family regulates pancreatic beta-cell survival in type 2 diabetes (Min6 cells)

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