Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Satoshi Kondo
PROVIDER: E-GEOD-58723 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Journal of virology 20141217 5
<h4>Unlabelled</h4>The Epstein-Barr virus (EBV) encodes its own microRNAs (miRNAs); however, their biological roles remain elusive. The commonly used EBV B95-8 strain lacks a 12-kb genomic region, known as BamHI A rightward transcripts (BART) locus, where a number of BART miRNAs are encoded. Here, bacterial artificial chromosome (BAC) technology was used to generate an EBV B95-8 strain in which the 12-kb region was fully restored at its native locus [BART(+) virus]. Epithelial cells were stably ...[more]