Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

32 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from prostate tumor of TRAMPxNOD/ShiLtJ F2 cross

ABSTRACT: We hypothesize that germline variation influences susceptibility to aggressive prostate tumor We examined the changes in gene expression in tumors obtain from TRAMPxNOD/ShiLtJ F2 mice in groups exhibiting metastasis versus no metastasis Transgene-positive (Tg+) F2 males were bred by crossing Tg- sires to Tg+ dames. 126 tumor samples were analyzed, which were obtained from the Tg+ F2 male

ORGANISM(S): Musculus

SUBMITTER: Kendra Williams

PROVIDER: E-GEOD-58829 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Expression data from prostate tumors of TRAMPxPWK/PhJ F2 cross

Project description:We hypothesize that germline variation influences susceptibility to aggressive prostate tumor We examined the changes in gene expression in tumors obtained from TRAMPxPWK/PhJ F2 mice Transgene-positive (Tg+) F2 males were bred by crossing Tg- sires to Tg+ dames. 27 tumor samples were analyzed, which were obtained from Tg+ F2 males

2015-12-15 | E-GEOD-61864 | biostudies-arrayexpress

Expression data from prostate tumor of TRAMPxNOD/ShiLtJ F2 cross

Project description:We hypothesize that germline variation influences susceptibility to aggressive prostate tumor We examined the changes in gene expression in tumors obtain from TRAMPxNOD/ShiLtJ F2 mice in groups exhibiting metastasis versus no metastasis

2015-06-25 | GSE58829 | GEO

Expression data from mammary tumors from a Diversity Outcross x PyMT mouse cross

Project description:Mouse genetic crosses were established between the PyMT model of metastatic breast cancer and the G5 generation of the Diversity Outcross (DO). Tumors were harvested from the animals for gene expression analysis to identify genes associated with progression to distant metastatic disease. Gene expression of 133 samples from the Diversity Outcross were assayed on Affymetrix chips.

2013-07-06 | E-GEOD-48565 | biostudies-arrayexpress

Expression data from mammary tumors from MOLF/Ei x PyMT mouse crosses and Diversity Outcross x PyMT mouse crosses

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-07-06 | E-GEOD-48566 | biostudies-arrayexpress

Expression data from mammary tumors from a MOLF/Ei x PyMT mouse cross

Project description:Mouse genetic crosses were established between the PyMT model of metastatic breast cancer and MOLF/Ei strain. Tumors were harvested from the animals for gene expression analysis to identify genes associated with progression to distant metastatic disease. Gene expression of 134 samples from the MOLF cross were assayed on Affymetrix chips.

2013-07-06 | E-GEOD-48564 | biostudies-arrayexpress

A macrophage autonomous Î±4Î²1integrin-Syk-Rac2 signaling axis controls macrophage differentiation, tumor growth and metastasis

Project description:Macrophages, play an essential role in promoting tumor growth by affecting angiogenesis, immune suppression, invasion and metastasis. The signal transduction events within macrophages which encode the complex cascade of events required for tumor growth and polarization of macrophages are poorly understood. We have discovered an ECM dependent signaling pathway in macrophages that regulates M2 macrophage differentiation, tumor growth, invasion and metastasis. We provide direct evidence that a macrophage autonomous, Î±4Î²1 integrin dependent Syk-Rac2 signaling axis acts in concert with the p110 isoform (PTEN-PI-3 kinase pathway) to control metastasis. SmoA1 Tg MB tumor cells were sorted into CD15+ and CD15- populations. RNA from these samples were hybridized to Affymetrix Mouse Genome 1.0 ST array.

2012-11-15 | E-GEOD-41717 | biostudies-arrayexpress

Sheep longissimus dorsi (LD) muscle from 40 individual progeny belonging to six Poll Dorset industry sires

Project description:Expression profiling of sheep born to Australian industry sires with high and low genetic merit (Estimated Breeding Values or EBVs) for eye muscle depth (EMD). Progeny (40) from six Poll Dorset sires representing well defined extremes of EBVs for Eye Muscle Depth (low EBV EMD and high EBV EMD) were selected for analysis. The six sires were Australian industry sires with three sires representative of low EBV EMD and three representing high EBV EMD. Microarrays were used for transcription profiling of skeletal muscle samples taken from 40 individual progeny belonging to six Poll Dorset industry sires, with 3 sires extreme for high and 3 sires extreme for low muscling (based on EBV for EMD). Sheep longissimus dorsi (LD) skeletal muscle samples were collected from 40 individual progeny belonging to six Poll Dorset industry sires, with 3 sires extreme for high and 3 sires extreme for low muscling (based on EBV for EMD).

2010-11-30 | E-GEOD-20552 | biostudies-arrayexpress

Mus musculus

Project description:Expression data from prostate tumor of TRAMPxNOD/ShiLtJ F2 cross

| PRJNA253601 | ENA

MRLxSM eQTL in Liver by RMA on Ensembl transcripts

2011-11-28 | GSE25322 | GEO

MRLxSM eQTL in Liver by RMA on Ensembl transcripts

Project description:A QTL analysis between inbred mouse strains MRL/MpJ and SM/J was performed to identify genetic loci influencing high-density lipoprotein (HDL) cholesterol and triglycerides (TG) at eight weeks of age in F2 mice fed a chow diet. In order to narrow down lists of candidate genes, expression levels from liver tissue were used to test for differential expression among parental and F1 strains and to scan for eQTL in F2 animals. We provide evidence for Mppe1 (Chr 18) as an HDL QTL candidate gene and Cyp2d26 (Chr 15) as a TG QTL candidate gene. MRL/MpJ (MRL) mice were crossed with male SM/J (SM) mice; their progeny were intercrossed to produce 371 F2 animals. Of these, 282 F2 males and females were profiled with Affy Mouse Gene 1.0 ST arrays for an eQTL study. Three animals from each parental and the F1 strains from each sex, i.e. 18 in total, were also profiled for testing differential expression. A total of 300 samples are included in the dataset. The mice were weaned at 3 weeks on a chow diet. At 13 weeks of age, mice were single housed for 3 days and fasted for 4 hours prior to being sacrificed. Tissue collection was performed between noon and 1pm to avoid variations due to circadian rhythm.

2011-11-28 | E-GEOD-25322 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data