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OSCC whole genome expression by T stage

ABSTRACT: Differentially expressed genes between T4 and T1 stage human oral squamous cell carcinoma (OSCC) 36 OSCC samples separated by tumor size T stage, in dual color microarray, using a pool of human cell lines as control. Screening for differentially expressed genes was performed in a cohort of 36 patients randomly selected. Transcriptional profiles were performed using Agilent one color hybridizations in a G4851A platform.

ORGANISM(S): Homo sapiens

SUBMITTER: Joao Paulo Oliveira-Costa

PROVIDER: E-GEOD-59069 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells.

Oliveira-Costa Joao Paulo JP de Carvalho Alex Fiorini AF da Silveira da Giorgia Gobbi da GG Amaya Peter P Wu Yongqi Y Park Kyoung-Joo Jenny KJ Gigliola Mabel Pinilla MP Lustberg Maryam M Buim Marcilei Eliza Cavicchioli ME Ferreira Elisa Napolitano EN Kowalski Luiz Paulo LP Chalmers Jeffrey J JJ Soares Fernando Augusto FA Carraro Dirce Maria DM Ribeiro-Silva Alfredo A

Oncotarget 20150801 25

Oral squamous cell carcinoma (OSCC) is the most common tumor of the oral cavity and has been associated with poor prognosis. Scarce prognostic markers are available for guiding treatment and/or sub-classifying patients. This study aims to identify biomarkers by searching for genes whose expression is increased or decreased during tumor progression (through T1 to T4 stages). Thirty-six samples from all tumor size stages (from T1 to T4) were analyzed using cDNA microarrays. Selected targets were a ...[more]

PMID: 26041877

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OSCC whole genome expression by T stage

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2018-04-25 | PXD005263 | Pride

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