Ontology highlight
ABSTRACT:
ORGANISM(S): Candida glabrata CBS 138
SUBMITTER: Thomas Bair
PROVIDER: E-GEOD-59839 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Antimicrobial agents and chemotherapy 20140908 11
The fungal pathogen Candida glabrata is an emerging cause of candidiasis in part owing to its robust ability to acquire tolerance to the major clinical antifungal drug fluconazole. Similar to the related species Candida albicans, C. glabrata most typically gains azole tolerance via transcriptional induction of a suite of resistance genes, including a locus encoding an ABCG-type ATP-binding cassette (ABC) transporter that is referred to as CDR1 in Candida species. In C. glabrata, CDR1 expression ...[more]