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Analysis of gene expression changes during long-term induction of EMT in EpRas tumor cells by TGF-b1.

ABSTRACT: EMT is a developmental process, which can be reactivated in cancer cells. Cancer cells maintaining EMT in the circulation may have pro-metastatic properties. We used microarrays to profile EMT-related gene expression changes after 14 d of TGF-b1 treatment. EpRas cells were cultured in standard conditions either in the presence of absence of recombinant TGF-b1 (2 ng/ml) for 14 d. After this period, RNA was isolated from triplicate wells of treated and non-treated cells, and hybridized on Affymetrix microarrays.

ORGANISM(S): Mus musculus

SUBMITTER: Jonas Fuxe

PROVIDER: E-GEOD-59922 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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