Unknown,Transcriptomics,Genomics,Proteomics

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Exosc8-Regulated Genes in Fetal Liver-Derived Erythroid Progenitor Cells


ABSTRACT: Exosc8 and Exosc9 are components of the exosome that establish a barricade to erythroid maturation. Here, we knocked down Exosc8 in fetal liver-derived erythroid progenitor cells to determine the cohort of Exosc8-regulated genes in erythroid cells. Freshly isolated fetal liver progenitor cells were infected with retrovirus expressing shRNA targeting either luciferase or Exosc8. Total RNA was isolated from these cells after 3 days ex-vivo culture, during which the cells underwent erythroid maturation.

ORGANISM(S): Mus musculus

SUBMITTER: Andrew DeVilbiss 

PROVIDER: E-GEOD-60136 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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