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Upregulation of CD11A on hematopoietic stem cells denotes the loss of long-term reconstitution potential

ABSTRACT: Comparison of gene expression patterns between phenotypic mouse HSCs (Lin- KIT+ SCA-1+ FLK2- CD150+ CD34-) separated into CD11A- and CD11A+ fractions. A link to our analysis of these populations can be found here (https://gexc.stanford.edu/model/1007). Mouse HSCs were subdivided based on expression of CD11A into positive and negative subfractions, and gene expression patterns analyzed by the Gene Expression Commons (gexc.stanford.edu)

ORGANISM(S): Mus musculus

SUBMITTER: Matthew Inlay

PROVIDER: E-GEOD-60597 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Upregulation of CD11A on hematopoietic stem cells denotes the loss of long-term reconstitution potential

Project description:Comparison of gene expression patterns between phenotypic mouse HSCs (Lin- KIT+ SCA-1+ FLK2- CD150+ CD34-) separated into CD11A- and CD11A+ fractions. A link to our analysis of these populations can be found here (https://gexc.stanford.edu/model/1007).

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