Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Expression data from cells overexpressing c19orf63 (HSS1)


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Katiana Junes-Gill 

PROVIDER: E-GEOD-61780 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis.

Junes-Gill Katiana S KS   Lawrence Chris E CE   Wheeler Christopher J CJ   Cordner Ryan R   Gill Tristan G TG   Mar Vernon V   Shiri Liron L   Basile Lena A LA  

BMC cancer 20141206


<h4>Background</h4>Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) is a truly novel protein, defining a new class of secreted factors. We have previously reported that ectopic overexpression of hHSS1 has a negative modulatory effect on cell proliferation and tumorigenesis in glioblastoma model systems. Here we have used microarray analysis, screened glioblastoma samples in The Cancer Genome Atlas (TCGA), and studied the effects of hHSS1 on glioma-derived cells and endothelial ce  ...[more]

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