Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Katiana Junes-Gill
PROVIDER: E-GEOD-61780 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Junes-Gill Katiana S KS Lawrence Chris E CE Wheeler Christopher J CJ Cordner Ryan R Gill Tristan G TG Mar Vernon V Shiri Liron L Basile Lena A LA
BMC cancer 20141206
<h4>Background</h4>Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) is a truly novel protein, defining a new class of secreted factors. We have previously reported that ectopic overexpression of hHSS1 has a negative modulatory effect on cell proliferation and tumorigenesis in glioblastoma model systems. Here we have used microarray analysis, screened glioblastoma samples in The Cancer Genome Atlas (TCGA), and studied the effects of hHSS1 on glioma-derived cells and endothelial ce ...[more]