Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-Seq Versus Oligonucleotide Array Assessment of Dose-Dependent TCDD-elicited Hepatic Gene Expression in Mice [Array]

ABSTRACT: Dose-dependent hepatic gene expression was examined following repeated exposure (every 4 days for 28 days) to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). These data were used to examine the effect of repeated TCDD exposure as well as compare the performance of RNA-Seq and Agilent oligonucleotide microarrays for detection and identificatioin of differentially expressed genes. Three biological replicates for each dose (0.01, 0.03, 0.1, 0.3, 1, 3, 10, 30) of TCDD and sesame oil vehicle This submission represents the Agilent microarrays component of study.

ORGANISM(S): Mus musculus

SUBMITTER: Timothy Zacharewski

PROVIDER: E-GEOD-62850 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

RNA-Seq Versus Oligonucleotide Array Assessment of Dose-Dependent TCDD-elicited Hepatic Gene Expression in Mice

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-02-10 | E-GEOD-62903 | biostudies-arrayexpress

Temporal examination of Clofibrate and WY-14,643 elicited gene expression in C57BL/6 mice

Project description:Temporal hepatic gene expression elicited by PPARα agonists Clofibrate and WY-14,643 was examined. These data were used to select PPARα regulated genes that may demonstrate species-specific regulation for assessment by QRT-PCR in a novel human adult stem cell model. Three biological replicates for each treatment were compared to time-matched vehicle control

2013-06-12 | E-GEOD-47844 | biostudies-arrayexpress

RNA-Seq Versus Oligonucleotide Array Assessment of Dose-Dependent TCDD-elicited Hepatic Gene Expression in Mice [RNA-Seq]

Project description:Dose-dependent hepatic gene expression was examined following repeated exposure (every 4 days for 28 days) to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). These data were used to examine the effect of repeated TCDD exposure as well as compare the performance of RNA-Seq and Agilent oligonucleotide microarrays for detection and identificatioin of differentially expressed genes. Five biological replicates for each dose (0.01, 0.03, 0.1, 0.3, 1, 3, 10, 30) of TCDD and sesame oil vehicle

2015-02-10 | E-GEOD-62902 | biostudies-arrayexpress

Molecular lung immunopathology of uncumplicated pdm H1N1 pneumonia in mice.

Project description:In this work we generated a no-letal mice model infected with pandemic H1N1 virus in order to study the mechanisms implicated in the resolution of uncomplicated pneumonia by using gene expression profiles of lung tissues.

2017-09-25 | E-MTAB-3866 | biostudies-arrayexpress

Transcription profiling by array of human CD56brightCD16-, CD56dimNKG2A+ and CD56dimNKG2A- natural killer cell subsets

Project description:CD56brightCD16-, CD56dimNKG2A+ and CD56dimNKG2A- NK cells subsets were FACS sorted and their transcriptional profile were compared after whole genome microarray analysis.

2010-08-10 | E-MEXP-2798 | biostudies-arrayexpress

Intubated patients developing Tracheobronchitis or Pneumonia have distinctive complement system gene expression signatures

Project description:The onset of an infection-specific transcriptional program precedes the clinical diagnosis in patients who developed Ventilator-associated pneumonia (VAP). Ventilator-associated tracheobronchitis (VAT) is another respiratory infection affecting<br><br>outcomes in intubated patients, but interactions between VAT and VAP remains unknown.

2011-11-19 | E-MEXP-3001 | biostudies-arrayexpress

Identification of differentially expressed genes in human alveolar bone cells cultured on different titanium surfaces.

Project description:To evaluate mRNA expression profile (transcriptome), we identified mRNAs of osteoblastic cells from human alveolar crest culture in contact with different titanium surfaces: control (polished), nanotextured (polished titanium discs, etching at 25oC with 50% H2SO4conc and 50% H2O2aq) , nano+submicrotextured (polished titanium discs, etching at 50oC with 50% H2SO4conc and 50% H2O2aq) and rough microtexture (polished titanium discs, etching at 50oC with 100% H2O2aq). The osteoblastic cells were cultured in the alpha-minimum essential medium, supplemented with fetal bovine serum, gentamicin, fungizone, dexamethasone, ascorbic acid and β-glycerophosphate. The mRNA expression profiling was analyzed through hybridizations with whole-human genome Agilent microarray (4x44K format).

2014-11-14 | E-MTAB-3091 | biostudies-arrayexpress

Identification of differentially expressed microRNA in human alveolar bone cells cultured on different titanium surfaces.

Project description:To evaluate miRNA expression profile (miRNOME), we identified microRNAs of osteoblastic cells from human alveolar crest culture in contact with different titanium surfaces: control (polished), nanotextured (polished titanium discs, etching at 25°C with 50% H2SO4conc and 50% H2O2aq) , nano+submicrotextured (polished titanium discs, etching at 50°C with 50% H2SO4conc and 50% H2O2aq) and rough microtexture (polished titanium discs, etching at 50°C with 100% H2O2aq). The osteoblastic cells were cultured in the alpha-minimum essential medium, supplemented with fetal bovine serum, gentamicin, fungizone, dexamethasone, ascorbic acid and β-glycerophosphate. The microRNA expression profiling was analyzed through hybridizations with Agilent miRNA-microarray (8x15K format).

2014-12-12 | E-MTAB-3093 | biostudies-arrayexpress

Transcription profiling of Solanum tuberosum tubers growing at different velocities

Project description:X-ray CT was used to determine the growth velocity of individual tubers. RNA was extracted from tubers growing at different velocities and used for microarray hybridisation.

2010-02-08 | E-MEXP-2484 | biostudies-arrayexpress

Expression analysis of meristematic tissue (Me) and young leaves (Le) isolated by manual dissection of clv3-9 plants

Project description:For the expression analysis of undifferentiated and differentiated tissues a meristem enriched fraction and young leaves (up to 3 mm leaf blade length) were isolated from clavata3-9 plants. Clavata3-9 mutants harbour larger shoot apical meristems than wild type plants enabling the preparation of meristematic tissue by manual dissection. Samples from both tissues were used for expression and histone H3 lysine 27 trimethylation (H3K27me3) analysis. Tissues for expression and H3K27me3 ChIP-chip analyses were simultaneously harvested. Meristem enriched samples (XMe1 and XMe2) and young leaf samples (XLe1 and XLe2) of clavata3-9 plants were isolated and hybridised to Agilent 44 k arrays [G2519F, V4 (Agilent, Santa Clara)]. Two biological replicates were performed.

2011-03-21 | E-GEOD-24464 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data