MiRNA profiling for mouse B10+ cells and B10- B cells
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ABSTRACT: we used genome-wide transcriptome analysis to profile the mRNA, long noncoding RNA (lncRNA), and microRNA (miRNA) expression of B10 cells, an antigen-specific Cd1dhiCd5+Cd19hiIl10 competent regulatory B cell. Potential key upstream regulators (including transcription factors, cytokines, trans-membrane receptors, and kinases) for Breg biogenesis and function were identified. B10+ B cells (Cd1dhiCd5+Cd19hiIl10+) and B10- cells (Cd1d-Cd5-Cd19hiIl10-) from mouse splenic B cell were sorted for RNA preparation. Two independent repeats were prepared for microarray analysis
ORGANISM(S): Mus musculus
SUBMITTER: Jianbo Sun
PROVIDER: E-GEOD-63374 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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