Expression data from CD1d tetramer-sorted b-GL122/LGL1âspecific human T cells or iNKT cells
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ABSTRACT: The ability to detect and isolate bGL1-22/LGL1âspecific human type II NKT cells allowed us to compare the global gene expression profiles of these cells with type I NKT cells using microarray analysis. Principal component analysis revealed that the gene expression profile signature for bGL1-22 and LGL1-specific T cells both before and after activation with anti-CD3/CD28 beads is distinct from that of type I NKT cells. RNA from CD1d tetramer-sorted b-GL122/LGL1âspecific T cells or iNKT cells was amplified, labeled, and hybridized on the Affymetrix Human Genome U133 Plus 2.0 microarray chips. The data were analyzed with GeneSpring GX 12.5 (Agilent Technologies)
ORGANISM(S): Homo sapiens
SUBMITTER: Rakesh Verma
PROVIDER: E-GEOD-77909 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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