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Genome-wide characterization of HSF1 binding in human 451Lu melanoma cancer cells under basal conditions

ABSTRACT: HSF1 orchestrates a transcriptional program vital for cancer cells. In this study we assayed for genome-wide localization of HSF1 enrichment in the 451Lu melanoma in untreated cells. These results revealed a transcriptional program enriched for metastasis-related genes. Twenty million cells were used for the ChIP and precipitated using 5 micrograms of antibody (cell signaling, 4356) against human HSF1

ORGANISM(S): Homo sapiens

SUBMITTER: Nikos Kourtis

PROVIDER: E-GEOD-63589 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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