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LPS timecourse

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE324: BMM_C3H/ARC_LPS_timecourse GSE325: BMM_BalbC_LPS_timecourse GSE326: BMM_C3H/HeJ_LPS_timecourse Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Timothy Ravasi

PROVIDER: E-GEOD-6435 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genetic control of the innate immune response.

Wells Christine A CA Ravasi Timothy T Faulkner Geoffrey J GJ Carninci Piero P Okazaki Yasushi Y Hayashizaki Yoshihide Y Sweet Matthew M Wainwright Brandon J BJ Hume David A DA

BMC immunology 20030626

<h4>Background</h4>Susceptibility to infectious diseases is directed, in part, by the interaction between the invading pathogen and host macrophages. This study examines the influence of genetic background on host-pathogen interactions, by assessing the transcriptional responses of macrophages from five inbred mouse strains to lipopolysaccharide (LPS), a major determinant of responses to gram-negative microorganisms.<h4>Results</h4>The mouse strains examined varied greatly in the number, amplitu ...[more]

PMID: 12826024

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