SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2
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ABSTRACT: We investigated the effect of SIRT6-knockout on gene expression and H3K4me3 modification profile in human mesenchymal stem cells. RNAs isolated from SIRT6+/+ and SIRT6-/- hMSCs at early and late passages were sequenced, respectively. And, H3K4me3 ChIP-seq was performed upon the SIRT6 deleted hMSC and WT at early stage, respectively.
ORGANISM(S): Homo sapiens
SUBMITTER: xiaomeng liu
PROVIDER: E-GEOD-64642 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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