Unknown,Transcriptomics,Genomics,Proteomics

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Expression data at each site in colon cancer


ABSTRACT: Colon cancer invade to depper layer and the expression of major molecules at cancer front change. But the screening of expression changing at cancer front has not be adequtely clarified. We compared gene expression at cancer front with it at cancer center. We got cancer cells from cancer front(F) and cancer center(C) by lasermicrodissection.

ORGANISM(S): Homo sapiens

SUBMITTER: Takaaki Kobayashi 

PROVIDER: E-GEOD-65480 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Microarray Analysis of Gene Expression at the Tumor Front of Colon Cancer.

Kobayashi Takaaki T   Masaki Tadahiko T   Nozaki Eriko E   Sugiyama Masanori M   Nagashima Fumio F   Furuse Junji J   Onishi Hiroaki H   Watanabe Takashi T   Ohkura Yasuo Y  

Anticancer research 20151201 12


Budding or the presence poorly differentiated clusters at the boundary of cancer tissue is a pathologically important finding and serves as a prognostic factor in colorectal cancer. However, few studies have examined the cancer tissue boundary in clinical samples. The purpose of the present study was to examine gene expression at the tumor front of colon cancer in surgically resected samples. Cancer tissues were obtained by laser microdissection of 20 surgically resected specimens. Genes with si  ...[more]

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