Transcription profiling of mouse Male A/JCr mice were inoculated with H. hepaticus or vehicle at 4 weeks some underwent castration at 1 year
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ABSTRACT: We are investigating hepatic transcriptional responses associated with castration and tumorigenic hepatitis induced by Helicobacter hepaticus infection in mature male A/JCr mice; Microarray data demonstrated a global loss of gender-dimorphic gene expression regulation in mice with chronic hepatitis and liver cancer Experiment Overall Design: Male A/JCr mice were inoculated with H. hepaticus or vehicle at 4 weeks; some underwent castration at 1 year, and all were necropsied at 21 months
ORGANISM(S): Mus musculus
SUBMITTER: Rebecca Fry
PROVIDER: E-GEOD-6632 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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