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Specific IMPC gene expression signature

ABSTRACT: Polarity defects are a hallmark of most carcinomas. Cells from invasive micropapillary carcinomas (IMPCs) of the breast are characterized by a striking cell polarity inversion and represent a good model for the analysis of polarity abnormalities. We have performed an in-depth investigation of polarity alterations in 24 IMPCs, compared with invasive carcinomas of no special type (ICNST). We used microarrays to compared gene expression profilings of IMPC with ICNST in a training set and in validation one. 124 breast cancer samples: 73 IMPC and 51 ICNST (training set: 63 samples and validation set: 61 samples)

ORGANISM(S): Homo sapiens

SUBMITTER: NadÃ¨ge GRUEL

PROVIDER: E-GEOD-66418 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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