Unknown,Transcriptomics,Genomics,Proteomics

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New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Mark Ibberson 

PROVIDER: E-GEOD-66429 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach.

Zufferey Anne A   Ibberson Mark M   Reny Jean-Luc JL   Nolli Séverine S   Schvartz Domitille D   Docquier Mylène M   Xenarios Ioannis I   Sanchez Jean-Charles JC   Fontana Pierre P  

Human genetics 20160216 4


Platelet reactivity (PR) is variable between individuals and modulates clinical outcome in cardiovascular (CV) patients treated with antiplatelet drugs. Although several data point to a genetic control of platelet reactivity, the genes contributing to the modulation of this phenotype are not clearly identified. Integration of data derived from high-throughput technologies may yield novel insights into the molecular mechanisms that govern platelet reactivity. The aim of this study is to identify  ...[more]

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