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Casein kinase II promotes target silencing by miRISC through direct phosphorylation of the DEAD-box RNA helicase CGH-1

ABSTRACT: In this study we show that global levels of mature miRNAs are unaffected in C. elegans after knockdown of either subunit of CK2 (encoded by kin-3 and kin-10) by RNAi. Small RNAs were quantified from wild-type animals at L4 stage fed either vector (L4440), kin-3, kin-10, or alg-1 RNAi. Mature miRNA counts were quantified by summing the total number of reads mapping to each miRNA and normalized to the total number of mapped reads per sequencing library.

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Mallory Freeberg

PROVIDER: E-GEOD-66764 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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