Dataset Information
Cerebellum Control (Alzheimer's disease control)
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Erin Heinzen
PROVIDER: E-GEOD-6778 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease.
Genome biology 20070101 3
<h4>Background</h4>Alternative gene transcript splicing permits a single gene to produce multiple proteins with varied functions. Bioinformatic investigations have identified numerous splice variants, but whether these transcripts are translated to functional proteins and the physiological significance of these alternative proteins are largely unknown. Through direct identification of splice variants associated with disease states, we can begin to address these questions and to elucidate their r ...[more]
