CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Vince Schulz
PROVIDER: E-GEOD-67893 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells.
Steiner Laurie A LA Schulz Vincent V Makismova Yelena Y Lezon-Geyda Kimberly K Gallagher Patrick G PG
PloS one 20160524 5
<h4>Background</h4>CTCF and cohesinSA-1 are regulatory proteins involved in a number of critical cellular processes including transcription, maintenance of chromatin domain architecture, and insulator function. To assess changes in the CTCF and cohesinSA-1 interactomes during erythropoiesis, chromatin immunoprecipitation coupled with high throughput sequencing and mRNA transcriptome analyses via RNA-seq were performed in primary human hematopoietic stem and progenitor cells (HSPC) and primary hu ...[more]
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