Unknown,Transcriptomics,Genomics,Proteomics

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Expression data from female reproductive organs of adult mice treated with estrogen


ABSTRACT: Estrogen induce organ-specific cell proliferation and development in female reproductive organs, though the reproductive differentiation, sex maturation, implantation and lactation. However, the mechanism of organ-specific estrogen responsive genes is unknown. Thus, we examined early estrogen responsive genes in mouse uterus, vagina and mammary gland. Keywords: organ specificity 70-day-old ovariectomized mice (C57BL/6J)(n=4) were treated with 17beta-estradiol (5micro g/kg) or sesame oil. Whole uterus (Ut), vagina (Vg) and mammary gland (Mg) were sacrificed 6h after the injection.

ORGANISM(S): Mus musculus

SUBMITTER: Suzuki Atsuko 

PROVIDER: E-GEOD-6931 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Comparison of estrogen responsive genes in the mouse uterus, vagina and mammary gland.

Suzuki Atsuko A   Urushitani Hiroshi H   Watanabe Hajime H   Sato Tomomi T   Iguchi Taisen T   Kobayashi Tomohiro T   Ohta Yasuhiko Y  

The Journal of veterinary medical science 20070701 7


Female reproductive organs are mainly regulated by estrogen and progesterone. Specifically, the uterus, vagina and mammary gland show organ-specific mitosis and morphological changes during proliferative events, such as estrous cycle, gestation and lactation. The mechanism underlying these organ-specific estrogen-dependent events is still unknown. We examined, therefore, global gene expression in the mature uterus, vagina and mammary gland of ovariectomized adult mice 6 hr after an injection of  ...[more]

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