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BMP signaling differentially regulates distinct hematopoietic stem cell types

ABSTRACT: In BRE-GFP transgenic mice BMP activated cells are marked by GFP expression. Analysis of GFP+ and GFP- LSK-SLAM HSC enriched fractions from fetal liver and adult bone marrow shows the interinsic differences in the genetic program of these two HSC enriched fractions. RNAseq of GFP+ and GFP- LSK-SLAM cells from BRE-GFP transgenic mice Fetal liver and adult bone marrow

ORGANISM(S): Mus musculus

SUBMITTER: Elaine Dzierzak

PROVIDER: E-GEOD-70132 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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BMP signaling differentially regulates distinct hematopoietic stem cell types

Project description:In BRE-GFP transgenic mice BMP activated cells are marked by GFP expression. Analysis of GFP+ and GFP- LSK-SLAM HSC enriched fractions from fetal liver and adult bone marrow shows the interinsic differences in the genetic program of these two HSC enriched fractions.

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