Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Christopher Gregg
PROVIDER: E-GEOD-70484 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Bonthuis Paul J PJ Huang Wei-Chao WC Stacher Hörndli Cornelia N CN Ferris Elliott E Cheng Tong T Gregg Christopher C
Cell reports 20150730 6
Here, we describe an RNA-sequencing (RNA-seq)-based approach that accurately detects even modest maternal or paternal allele expression biases at the tissue level, which we call noncanonical genomic imprinting effects. We profile imprinting in the arcuate nucleus (ARN) and dorsal raphe nucleus of the female mouse brain as well as skeletal muscle (mesodermal) and liver (endodermal). Our study uncovers hundreds of noncanonical autosomal and X-linked imprinting effects. Noncanonical imprinting is h ...[more]