Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

ACTG A5258 Clinical administration of chloroquine to patients with untreated chronic HIV infection to reduce immune activation


ABSTRACT: ACTG A5258, we asked whether chloroquine could reduce the immune activation in HIV infection posited to be driven by microbial TLR agonists, such as bacterial elements translocated from the gut and HIV-1 RNAs . We anticipate that blocking this activation pathway might interfere with events in pathogenesis leading to AIDS- and non-AIDS-related clinical manifestations of HIV disease. Blood samples were taken from 20 individuals at week 0 (before treatement) and week 12. 10 individuals received chloroquine 250mg orally and 10 individuals received placebo.

ORGANISM(S): Homo sapiens

SUBMITTER: Gregory Tharp 

PROVIDER: E-GEOD-71063 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2016-07-15 | E-GEOD-71064 | biostudies-arrayexpress
2016-07-15 | GSE71064 | GEO
2016-07-15 | GSE71063 | GEO
2007-10-12 | E-MEXP-1201 | biostudies-arrayexpress
2023-12-11 | PXD046662 | Pride
2011-08-01 | E-GEOD-30867 | biostudies-arrayexpress
2012-06-30 | E-GEOD-30351 | biostudies-arrayexpress
2012-01-18 | GSE24579 | GEO
2012-01-18 | E-GEOD-24579 | biostudies-arrayexpress
2022-03-31 | ST002133 | MetabolomicsWorkbench