Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Genome wide analysis of liver histone H3K9 acetylation after partial hepatectomy in glucose-treated and control mice.

ABSTRACT: We report the results of AcH3K9 ChIP-Seq on regenerating liver harvested 12 h after partial hepatectomy (PH) from mice treated with supplemental parenteral dextrose (to delay onset of PH-induced hypoglycemia) or vehicle (as control). Examination of the effect of delaying PH-induced hypoglycemia on histone H3K9 acetylation in regenerating liver.

ORGANISM(S): Mus musculus

SUBMITTER: Paul Cliften

PROVIDER: E-GEOD-71496 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration.

Huang Jiansheng J Schriefer Andrew E AE Cliften Paul F PF Dietzen Dennis D Kulkarni Sakil S Sing Sucha S Monga Satdarshan P S SP Rudnick David A DA

The American journal of pathology 20160106 3

All serious liver injuries alter metabolism and initiate hepatic regeneration. Recent studies using partial hepatectomy (PH) and other experimental models of liver regeneration implicate the metabolic response to hepatic insufficiency as an important source of signals that promote regeneration. Based on these considerations, the analyses reported here were undertaken to assess the impact of interrupting the hypoglycemic response to PH on liver regeneration in mice. A regimen of parenteral dextro ...[more]

PMID: 26772417

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Dataset Information

Genome wide analysis of liver histone H3K9 acetylation after partial hepatectomy in glucose-treated and control mice.

Publications

Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration.

Similar Datasets

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