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E12.5 distal forelimb embryonnic transcriptome

ABSTRACT: Analysis of gene expression in the distal forelimbs RNA-Seq polyA on transcripts extracted from the dissection of three pairs of embryonnic forelimbs at E12.5

ORGANISM(S): Mus musculus

SUBMITTER: Marion LELEU

PROVIDER: E-GEOD-72285 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states.

Fabre Pierre J PJ Benke Alexander A Joye Elisabeth E Nguyen Huynh Thi Hanh TH Manley Suliana S Duboule Denis D

Proceedings of the National Academy of Sciences of the United States of America 20151026 45

Chromatin condensation plays an important role in the regulation of gene expression. Recently, it was shown that the transcriptional activation of Hoxd genes during vertebrate digit development involves modifications in 3D interactions within and around the HoxD gene cluster. This reorganization follows a global transition from one set of regulatory contacts to another, between two topologically associating domains (TADs) located on either side of the HoxD locus. Here, we use 3D DNA FISH to asse ...[more]

PMID: 26504220

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E12.5 distal forelimb embryonnic transcriptome

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