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Response of peripheral blood mononuclear cells from young (â¤ 45 years old) and old (>60 years old) healthy donors to influenza virus derived peptide stimulation.

ABSTRACT: CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 11 young (â¤ 45 years old) and old (> 60 years old) healthy donors. The cells were stimulated with peptides derived from influenza virus for 24 hours. Unstimulated cells were cultured without the peptides for 24 hours.

ORGANISM(S): Homo sapiens

SUBMITTER: Scott Presnell

PROVIDER: E-GEOD-72374 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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