Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

MRNA Expression data from rats treated with ANIT or vehicle


ABSTRACT: Adult Sprague Dawley rats were treated i.g. with 50 mg/kg alpha-naphthylisothiocyanate (ANIT) or vehicle (corn oil). Hepatobiliary liver injury occurred at 24 h postdose in ANIT rats with repair at 120h. Livers were extracted from rats at 24h and 120 h post ANIT exposure. This study investigated differences in mRNA expression between the injury and repair phases in the context of ANIT exposure. 8 week male Sprague Dawley rats were administered ANIT or vehicle for quantification of hepatobiliary injury via clinical chemistry biomarkers and pathology between 6 and 168 h postdosing. Rats sacrificed at 24 h and 120h postdosing coincided with peak injury and injury resolution, respectively.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Alison Harrill 

PROVIDER: E-GEOD-72387 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2008-10-20 | E-GEOD-11097 | biostudies-arrayexpress
2013-07-12 | E-GEOD-48802 | biostudies-arrayexpress
2013-06-04 | E-GEOD-47618 | biostudies-arrayexpress
2023-08-31 | PXD034438 | Pride
2013-07-12 | E-GEOD-48803 | biostudies-arrayexpress
2008-11-24 | E-GEOD-13550 | biostudies-arrayexpress
2016-06-01 | E-GEOD-79017 | biostudies-arrayexpress
2005-12-22 | E-GEOD-3175 | biostudies-arrayexpress
2015-12-31 | E-GEOD-75656 | biostudies-arrayexpress
2021-04-23 | PXD023273 | Pride