Identification of c-myc target genes by siRNA
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Louis Staudt
PROVIDER: E-GEOD-7245 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Molecular diagnosis of Burkitt's lymphoma.
Dave Sandeep S SS Fu Kai K Wright George W GW Lam Lloyd T LT Kluin Philip P Boerma Evert-Jan EJ Greiner Timothy C TC Weisenburger Dennis D DD Rosenwald Andreas A Ott German G Müller-Hermelink Hans-Konrad HK Gascoyne Randy D RD Delabie Jan J Rimsza Lisa M LM Braziel Rita M RM Grogan Thomas M TM Campo Elias E Jaffe Elaine S ES Dave Bhavana J BJ Sanger Warren W Bast Martin M Vose Julie M JM Armitage James O JO Connors Joseph M JM Smeland Erlend B EB Kvaloy Stein S Holte Harald H Fisher Richard I RI Miller Thomas P TP Montserrat Emilio E Wilson Wyndham H WH Bahl Manisha M Zhao Hong H Yang Liming L Powell John J Simon Richard R Chan Wing C WC Staudt Louis M LM
The New England journal of medicine 20060601 23
<h4>Background</h4>The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is crucial because these two types of lymphoma require different treatments. We examined whether gene-expression profiling could reliably distinguish Burkitt's lymphoma from diffuse large-B-cell lymphoma.<h4>Methods</h4>Tumor-biopsy specimens from 303 patients with aggressive lymphomas were profiled for gene expression and were also classified according to morphology, immunohistochemistry, and detecti ...[more]
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