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Effect of muscle-specific ATF4 gene knockout (ATF4 mKO) on skeletal muscle mRNA levels in aged mice.

ABSTRACT: For additional details see Ebert et al, Identification and Small Molecule Inhibition of an ATF4-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. Quadriceps femoris muscles were harvested from 22-month-old muscle-specfic ATF4 knockout (ATF4 mKO) mice and littermate controls. mRNA levels in ATF4 mKO muscles were normalized to levels in littermate control muscles.

ORGANISM(S): Mus musculus

SUBMITTER: Scott Ebert

PROVIDER: E-GEOD-72658 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Effect of ATF4 gene knockout on skeletal muscle mRNA levels in fasted mice.

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RNA-Seq experiment to identify genes regulated by ATF4

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