The influence of menstrual cycle and endometriosis on endometrial methylome
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Merli Saare
PROVIDER: E-GEOD-73950 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The influence of menstrual cycle and endometriosis on endometrial methylome.
Saare Merli M Modhukur Vijayachitra V Suhorutshenko Marina M Rajashekar Balaji B Rekker Kadri K Sõritsa Deniss D Karro Helle H Soplepmann Pille P Sõritsa Andrei A Lindgren Cecilia M CM Rahmioglu Nilufer N Drong Alexander A Becker Christian M CM Zondervan Krina T KT Salumets Andres A Peters Maire M
Clinical epigenetics 20160112
<h4>Background</h4>Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes, and the menstrual cycle phase-dependent epigenetic signature should be considered when studying endometrial disorders. So far, no studies have been performed to evaluate the menstrual cycle influences and endometriosis-specific endometrial methylation ...[more]
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