PACAP dependency of genes regulated in adrenal gland
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Babru Samal
PROVIDER: E-GEOD-7405 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Meta-analysis of microarray-derived data from PACAP-deficient adrenal gland in vivo and PACAP-treated chromaffin cells identifies distinct classes of PACAP-regulated genes.
Samal Babru B Gerdin Matthew J MJ Huddleston David D Hsu Chang-Mei CM Elkahloun Abdel G AG Stroth Nikolas N Hamelink Carol C Eiden Lee E LE
Peptides 20070619 9
Initial PACAP-regulated transcriptomes of PACAP-treated cultured chromaffin cells, and the adrenal gland of wild-type versus PACAP-deficient mice, have been assembled using microarray analysis. These were compared to previously acquired PACAP-regulated transcriptome sets from PC12 cells and mouse central nervous system, using the same microarray platform. The Ingenuity Pathways Knowledge Base was then employed to group regulated transcripts into common first and second messenger regulatory clust ...[more]
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